Pethidine, also known as meperidine, is a synthetic opioid pain medication that is used to relieve moderate to severe pain. It works by binding to specific receptors in the brain and spinal cord to reduce pain perception. It can be administered orally, intravenously (IV), intramuscularly (IM), or subcutaneously (SC). Here is some information about its uses, dosage, administration, and side effects:
Uses:
- Pain relief: Pethidine is used to treat moderate to severe pain caused by surgery, injury, cancer, or other conditions.
- Obstetric analgesia: Pethidine is sometimes used during labor to relieve pain.
Dosage:
The dosage of pethidine depends on various factors such as the severity of pain, the patient’s age, weight, and medical history. The usual adult dose of pethidine is 50-150mg every 3-4 hours, not to exceed 600mg in 24 hours. The dosage for children is based on their weight.
Administration:
Pethidine can be administered orally, intravenously (IV), intramuscularly (IM), or subcutaneously (SC). The route of administration depends on the patient’s condition and the severity of pain. In acute pain management, the intravenous route is preferred for faster onset of action.
Side effects:
Pethidine can cause various side effects, including:
- Nausea and vomiting
- Dizziness and lightheadedness
- Sedation and drowsiness
- Confusion and hallucinations
- Respiratory depression (breathing difficulties)
- Allergic reactions (rash, itching, swelling)
- Hypotension (low blood pressure)
- Gastrointestinal disturbances (constipation, dry mouth)
It is important to inform your healthcare provider about any allergies or medical conditions before taking pethidine. Pethidine can be habit-forming, so it should be used only as prescribed and not shared with others.